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Ada Yonath

Ada Yonath

2009 Nobel Prize in Chemistry
Intro
Israeli crystallographer and Professor in Department of Structural Biology, Weizmann Institute of Science. In 2009, she was rewarded the Nobel Prize in Chemistry along with Venkatraman Ramakrishnan and Thomas A. Steitz for her studies on the structure an
Education and Work Experience
  • 1968, She obtained her Ph.D. from the Weizmann Institute of Science.
  • 1969-1970, Postdoctoral research at Carnegie Mellon University and MIT
  • 1988-Present, Professor of structural biology at the Weizmann Institute of Science
Honors and Awards
    • 2003,Foreign associate of the United States National Academy of Sciences
    • 2006, Wolf Prize in Chemistry
    • 2009, Nobel Prize in Chemistry

Major Academic Achievements

Protein plays a key role in life activities. Ribosomes are molecular machines for protein synthesis in organisms.

Professor Yonath focused on the X ray crystallography of ribosomes, determined the high-resolution three-dimensional structure of the ribosome, confirmed the channel of the new protein synthesis, and found the universal symmetric region to guide the polypeptides polymerization process, and revealed the extension capture (elongation arrest) in the process of the ribosome synthesis protein. The dynamic process of gating, intracellular regulation, and transportation of protein nascent chains elucidates the mechanism of protein synthesis. In order to carry out the crystallographic study of ribosomes, Professor Yonath pioneered the establishment of cryogenic crystallography, which is now widely used in structural biology for some complex research projects.